Although Cardarine GW501516 is not a true SARM, it is treated like one due to its Cardarine results.
In fact, multiple Cardarine reviews and studies indicate that it is used for:
1 – Energy – by stimulating glucose uptake, Cardarine enables your body to use glucose as its primary fuel source, which increases your energy levels, allowing you to exercise for longer periods of time.
2 – Fat Burning – Cardarine achieves this in three ways: 1) by stimulating glucose, which increases your fat-burning abilities, 2) by removing fat from your body's stores (which conserves carbohydrates), and 3) by activating fat-burning and carnitine genes (ABCA1 and CPT1). The combination of these can help keep you fit.
The science: One study in 13 men found decreased triglycerides, fatty acids, and VLDL proteins. In two separate studies, when participants took 5–10 mg of Cardarine for 12 weeks, researchers observed increased HDL cholesterol (in 305 participants) and decreased LDL and APOB.
3 – Mass gaining and cutting cycles – Cardarine is often used stacked with other SARMs and performance enhancing drugs to help prevent muscle loss (in a calorie deficit) and promote muscle gains.
4 – Brain – Cardarine, as a PPAR-delta inhibitor, can protect cerebral vessels from oxidative stress and damage, helping maintain blood flow to the brain. It has pro- and anti-inflammatory effects while enhancing nerve cell development.
5 – Obesity – A study of six overweight volunteers observed a reduction in metabolic syndrome symptoms and increased fat burning and muscle carnitine after taking 2.5 or 10 mg of Cardarine daily for two weeks. Cardarine also helped reduce liver fat by 20%, insulin by 11%, and blood fat by 23–30%, and inhibited the activity of inflammatory substances in adipose tissue through PPAR delta activation. This helps reduce chronic inflammation and insulin resistance associated with obesity.
6 – Heart and blood vessels – It's thought that Cardarine may have a direct effect on your blood vessels. This reduces plaque buildup in your arteries and increases nitric oxide levels. Low doses of Cardarine may reduce the risk of heart disease by reducing tissue damage and inflammation in your arteries.
7 – Kidneys – May reduce kidney inflammation (by reducing MCP-1 activity responsible for kidney disease).
8 – Liver Damage – One of the main things Cardarine targets is your liver. This is because your liver is important for storing, burning, and releasing fat into the body. It switches your energy source from glucose to fatty acids (through PPAR-delta activation). It also prevents insulin resistance in liver cells and protects your liver from damage when used short-term.
9 – Muscle growth and endurance – By activating PPAR-delta, Cardarine can promote the development of muscle fibers, nearly doubling your energy and endurance levels.
10 – Skin diseases – PPAR-delta activation can improve inflammation in skin cells caused by skin diseases such as psoriasis.
11 – Wound healing – by increasing nitric oxide levels, it can help optimize blood flow and improve wound healing.
How does Cardarine work?
Cardarine works by binding to and activating PPAR-delta in your cells (especially in your muscles), or stimulating the genes responsible for energy use.
By doing this, Cardarine can: increase your energy levels; speed up your metabolism; burn more fat; build your muscles; improve cholesterol, heart health and physical performance; reverse Type II diabetes and reduce the presence of lipids in your blood.
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